New homoeopathic drugs show results against cancer in lab model: Researchers
New drugs developed from Cancer tissues show anti-cancer effects in studies at ACTRECT (Tata) Institute, Mumbai; Study at Tata show initial results.
A scientific breakthrough in the field of homoeopathy research for cancer treatment in India could potentially change the way the world perceives cancer treatment. The research was conducted at Tata Memorial’s research facility ACTREC under the care of Dr Rajesh Shah, a Mumbai based homoeopath. Cancer claimed 9.6 million lives in the world in 2018 and India’s share was a worrying 8.17 per cent, according to statistics from World Health Organizations (WHO) International Agency for research on cancer.
The research done at the lab level was successfully conducted for three new drugs including Cancer Nosode which have been developed by Dr Rajesh Shah, from five types of different cancer tissues. The study has shown positive effects of high dilution, potentized medicines which are often criticized for lack of scientific evidence. The breakthrough has been lauded as the first of its kind in over fifty years in the field of homoeopathy. Dr Rajesh Shah who was feted with the National Award by the Ministry of AYUSH last year for another drug-discovery is the brain behind this path-breaking study in the field of homoeopathy.
Dr Rajesh Shah, MD (Hom) sharing his insight on the research said, “I have been working on developing new homoeopathic drugs for over two decades. Nosode is one of my major areas of interest. Cancer is a major challenge affecting millions of people in India and the numbers have seen a significantly sharp rise in the last few years. I decided to work towards scientifically developing the Cancer Nosode, which could fight cancer cells. The development process started many years ago. In my opinion and experience, no single system of medicine has a foolproof protocol to fight cancer. In my experience, homoeopathy has the potential to support cancer treatment. I believe the initial results are encouraging.”
Dr Shah’s experiments in the last two decades in laboratory models, animal studies, and human trials have shown irrefutable scientific evidence. Interestingly, scientists at IIT-B headed by Dr Jayesh Bellare, a chemist, have shown the nanoparticles of the source materials in high-dilution homoeopathic medicines, which were earlier believed to be containing some kind of ‘energy’.
“Homeopathy, originally born in Germany, is getting a scientific face-lift and India is a leader in this revolution,” said Dr Rajesh Shah.
Dr Raj K Manchanda, Former Director-General of CCRH (Central Council for Research in Homeopathy), under Ministry of AYUSH said, “Nosodes prepared from germs and diseased tissues are commonly used in homoeopathic practice. Dr Shah has scientifically developed new Nosodes from specific cancer tissues as well as a certain virus, using modern techniques. The Cancer Nosode, the HIV Nosode and the Hepatitis C Nosode demonstrate anti-cancer efficacy in cell-line models is strong preliminary evidence towards opening up many new research avenues. Further validation using this Nosode in animal and human models must be explored. I am happy that new homoeopathy drug research is done in India and that too by a practising homoeopath.”
In the past, in a collaborative project of CCRH with Bose institute, Kolkata scientists have shown and published the effect of traditional homoeopathic drugs in different cell lines. Even the mechanism of action of these drugs was elucidated. These developments are very important to enrich the scientific basis of homoeopathy.”
Dr Vedang Murthy, a radiation oncologist, and researcher at Tata Memorial Hospital Mumbai observed, “Cancer is a very difficult disease to treat and we are always on the lookout for new approaches in its treatment. Early research in the laboratory with a drug prepared from cancer tissues has shown activity against cancer cells. Dr Shah has shown preliminary results which should be strengthened by further research. These results may indicate some efficacy of homoeopathy in the laboratory model. This seems like an early exploration of untapped potential of homoeopathy against cancer.”
The initial scientific testing and experiments were done at ACTRECT (Tata) Institute, Mumbai. A total of three drugs were prepared from Cancer tissues, HIV Virus, and Hepatitis C Virus. The drugs show effective inhibition of growth in cancer cells. The homoeopathic drugs show anti-cancer activity on cell lines related to the liver, cervix, breast, and lung cancers. The anti-cancer activity was measured as percentage growth inhibition. Earlier, HIV Nosode and Hepatitis C Nosode have also shown specific anti-disease and anti-cancer effects in Dr Shah’s preliminary studies in coordination with Dr A.R. Khuda-Bukhsh, an eminent molecular biologist from Kalyani University, West Bengal. The recent study has strengthened the efficacy of the research. Since HIV and Hepatitis C viruses are potentially cancer-producing substances, Dr Shah has explored their effects against cancer successfully. The projects were aimed at reviewing the research-question of the efficacy of homoeopathic medicines against cancer, in potentized form using the standard laboratory model for cancer research.
Research papers have been published in international peer-reviewed journals and presented at prestigious conferences. The scientific monographs have been submitted to the concerned government departments for regulatory evaluation.
In the recent past, Dr Shah has collaborated with about 35 scientists from seven institutions such as Haffkine Institute, ICT, Nair, Tata, Nair Hospital, IIT-B, etc. for experiments related to new drug research.
The study has once more created scientific evidence of the effects of homoeopathic medicines in a laboratory model, as well as supported The Law of Similars (like cures like), the fundamental principle of homoeopathy. The Nosodes are homoeopathic drugs prepared from bacteria, virus, and diseased tissues, using a unique process called ‘potentization’ which renders the drugs to be safe yet effective. Such Nosodes have been in use in homoeopathy for over 180 years. The HIV Nosode was also developed by Dr Shah through a similar process as per the dictates of Dr Hahnemann, the founder of Homeopathy. Nosodes are not vaccines but are known to be effective against many diseases.
The results have ignited a new hope towards fighting the deadly malady of cancer. As per the fundamental principle of homoeopathy, vaccine, and hormesis, any substance having a capacity to produce specific disease also has a possibility to treat the same condition, if treated with a certain dose.
The market size for homoeopathy medicines in India is currently over one thousand crores, which has been growing by 15-20 per cent annually. India is the only country with a dedicated Ministry to handle Homeopathy, Ayurveda, and other alternative systems of medicine. India has the potential of becoming a world leader in this discipline.